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ZENODO
Preprint . 2026
License: CC BY
Data sources: ZENODO
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Preprint . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Preprint . 2026
License: CC BY
Data sources: Datacite
ZENODO
Preprint . 2026
License: CC BY
Data sources: Datacite
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From Imperfection by Perfection to Perfection by Imperfection: Universal Quality of Life Preserves Human Diversity

Authors: Yamada, Kenji;

From Imperfection by Perfection to Perfection by Imperfection: Universal Quality of Life Preserves Human Diversity

Abstract

As human enhancement—germline editing, neural interfaces, advanced prosthetics—moves towardreality, it generates a pressure easily overlooked: the optimization of the human toward a sharedideal contracts the range of genetic and cognitive variation. The process is gradual, diffuse, andunauthored, and its endpoint is an irreversible narrowing of the variation on which an unforeseenfuture might depend. The intuitive remedy is preservation, the banking of the variants we still hold.This paper argues that preservation cannot do the work asked of it: storage sorts by wealth, and atthe point of use it forces a ranking of variants that reinstates the eugenic sorting it was meant toavoid. Nor can the loss be averted by selecting more wisely. Because the value of a trait is relative toenvironments that cannot be known in advance, which traits are superior cannot be seen ahead oftime; optimization toward a single ideal is therefore not merely ethically hazardous butepistemically unfounded. The paper's positive claim is that human diversity is protected not byranking lives but by a universal quality of life: a social condition, combining technical compensationwith the valorization of atypical constitutions, under which every way of being human can live well.Where no constitution carries a penalty, the motive to select dissolves rather than having to beforbidden. The argument inverts a familiar assumption: the pursuit of perfection yields fragility,while the acceptance of imperfection yields the resilience that perfection itself could not secure.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green