This study offers a fresh theological and contextual interpretation of Acts 10:38, focusing on Luke’s portrayal of Jesus as a Spirit-anointed agent of goodness, healing, and liberation. Rather than treating the verse as a summary of miraculous activity alone, the article argues that Acts 10:38 functions as a deliberate Lukan redefinition of benefaction and leadership. Against the backdrop of Greco–Roman patronage systems, Luke presents Jesus as a divinely authorized benefactor whose actions resist honor-seeking, reciprocity, and hierarchical domination. Through exegetical analysis, socio-rhetorical reading, and African biblical hermeneutics, the study demonstrates that Jesus’ philanthropy is restorative, inclusive, and justice-oriented. When read within contemporary African religious contexts—marked by prosperity-driven religiosity, patronage leadership, and weak accountability—Acts 10:38 emerges as a normative theological critique. The article contends that authentic African Christian leadership should be reoriented toward servant leadership, ethical stewardship, community empowerment, and holistic human flourishing grounded in the Spirit’s work rather than personal charisma or material exchange.