Currently, there is a range of Nature-based Solutions (NbS) emerging, primarily supported by strong public funding, but significant gaps remain in understanding what drives or limits their demand and supply, and how to mainstream them within specific value chains. Closing this gap is essential for developing targeted policies, financial tools, and attracting private sector investment at scale. This report examines the integration of NbS into economic value chains in Europe, highlighting barriers and enablers for scaling and market development. It presents insights of the Invest4Nature (I4N) systematic literature review on demand and supply chain of NbS, including the role of different sectors in NbS implementation, replication and upscaling.It highlights: Key sectors driving supply and demand for NbS Drivers and barriers for NbS uptake Policy recommendations to support NbS growth