In a previous government commission, the Swedish Agency for Work Environment Expertise mapped and summarised existing research on the organisational and social work environment of LGBTQ people. The original Swedish version of the report “The Organisational and Social Work Environment of LGBTQ People – A Systematic Literature Review” was submitted to the Swedish Government on 30 June 2022. This guide is based on and summarises the most important aspects of the report. The guide is suitable reading for everyone who wants to get an overview of important issues and aspects related to the creation of a good work environment for LGBTQI people. The content of the guide is primarily aimed at work organisations, but certain parts can also be used by other types of organisations, such as non-profit associations or schools. While the guide’s content deals with Swedish employers’ responsibility to adhere to work environment and discrimination laws in this country, much of it is relevant to workplaces in other countries, as well.