The energy strategy 2050 of Switzerland is aiming at a substantial reduction of the consumption of not renewable energy and of energy sources, which are harmful for the climate, the environment and humans. The research project “Energy efficient and CO2-free Urban Logistics” aims at estimating and evaluating the potential of a more efficient use of energy, a reduction of CO2-emissions and the substitution of non-renewable energy resources regarding urban logistics in Switzerland. Possible developments in urban logistics and their impact on energy consumption and CO2-emission are shown in a scenario analysis. Furthermore a vision 2050 has been developed which fulfils the challenging targets for an “Energy efficient and CO2-free Urban Logistics” in Switzerland. The scenario analysis was completed in October 2016 and the vision has been carried out between November 2016 and June 2017. Based on the vision an action plan will be developed until end of 2017.