Background: Polycystic Ovary Syndrome is a common endocrine disorder that is characterized by the presence of chronic anovulation, excess levels of androgen as well as polycystic ovary on ultrasonographic imaging. Objectives: To determine the causes, complications and clinical features of polycystic ovary syndrome. To assess the anthropometric measurements of obesity in polycystic ovary syndrome Saudi women and to provide treatment for the associated obesity. Review of Literature: Polycystic Ovary Syndrome involves interactions between different components such as the anterior pituitary gland, hypothalamus, ovaries, suprarenal glands and peripheral fatty tissues. It seems to be a multifactorial disease. It presents with different manifestations and it can affect the metabolic and reproductive functions as well as the cardiovascular system. Abdominal obesity can initiate the pathogenesis of Polycystic Ovary Syndrome and the opposite is true. Clinical features, laboratory tests and ultrasound imaging are the clinical diagnosis. There is a high incidence rate within Saudi population due to increasing obesity. It has a significant effect on anthropometric body profiles of Saudi women. However, lifestyle modifications and pharmacological therapies have an essential role in management of obesity related to this syndrome. Conclusion: The etiology of Polycystic Ovary Syndrome is multifactorial and is linked to long term complications that present with cardinal features. It is significantly associated with high anthropometric findings in Saudi Arabian women, but lifestyle interventions and pharmacotherapy are effective in losing weight.