Abstract: Cucurbita moshchata is worldwide in distribution and rich in carotenoids, vitamins, dietary fiber , minerals and phenolic compounds .It has also medicinal values . .Pumpkin (Cucurbita moshchata L.) is an economically important food resource cultivated due to its nutritional composition. It has been used traditionally both as Humans and animal feed, also has Ethnomedicinal potential. It is cultivated throughout the world specialy in tropical area of Asia, Africa and America. Pumpkin fractions are rich source of nutritional components like oils, proteins, carbohydrates and minerals. Moreover, plant derived by-products with proper handling, may represent a low cost source of bio-active compounds potentially important for Pharmaceuticals and cosmetics industries. The study confirms the potential application of peel extracts of Pumpkin from Cucurbita species in dermatology