Our work is devoted to the development of new effective and environmentally friendly wheat growth regulators based on chemical nitrogen-containing heterocyclic compounds, thienopyrimidine derivatives. A comparative analysis of the regulatory effect of thienopyrimidine derivatives and the plant hormone auxin IAA, as well as plant growth regulators Methyur and Kamethur on the growth and photosynthesis of wheat (Triticum aestivum L.) variety Tyra was carried out. Growth parameters such as average shoot and root length (mm) and photosynthesis parameters such as content of photosynthetic pigment (μg/ml) of wheat grown from seeds soaked in water 10-7M solution of thienopyrimidine derivative were significantly increased after 3 weeks compared to those of control wheat plants grown from seeds soaked in distilled water. The regulatory effect of thienopyrimidine derivatives on the growth and photosynthesis of wheat was similar to the effect of the plant hormone auxin IAA and growth regulators Methyur and Kamethur used in a similar concentration of 10-7M in water solution for seed treatment. The most physiologically active thienopyrimidine derivatives were selected and the relationship between their chemical structure and regulatory effect on the growth and photosynthesis of wheat plants was analyzed. The proposed mechanisms of regulatory effect at the physiological and molecular levels of chemical nitrogen-containing heterocyclic compounds, thienopyrimidine derivatives on plant growth are discussed.