Purpose: ICT is currently considered as an integral part of the teaching and learning process. In the current age of technology, the use of ICT is very common in the field of education. The present study is conducted to the perception of teachers and trainee-teachers in teaching and learning process through ICT of teachers' training colleges and the perception is based on understanding the content, mindful lesson, and curriculum development. Through ICT, the teaching and learning process is conducted in a flexible manner. Methodology: The researchers have taken descriptive survey method for this study. The sample has consisted 100 teachers and 100 trainee-teachers from 10 teachers' training colleges which are selected randomly to complete this quantitative study based on survey questionnaire. A self-structured closed ended questionnaire with 5-point Likert type scale has used to collect data. Data collection process has done from primary and secondary sources both. The researchers have collected data by the respondents through e-mails, social sites, and telephonic conversations for this study. Collected data is analysed by various statistical techniques both as descriptive statistics and inferential statistics through Microsoft Excel 2007 software. Findings: It is found that no significant difference has revealed between the teachers and trainee-teachers' perception towards understanding the content, mindful lesson, and curriculum development through ICT. Teachers and trainee-teachers are able to better comprehend the teaching and learning process through ICT. Trainee-teachers are a bit more motivated than teachers to understand the content through ICT, moreover, trainee-teachers are more affected than teachers in the case of mindful lesson, and on the other hand, teachers tend to have a more lively-spontaneous attitude than trainee-teachers when it comes to curriculum development through ICT in teaching and learning process. Conclusion: This is given as the conclusion of the study, nowadays, it is very necessary to recitation through ICT along with our formal education. It is very easy to make the learning topics meaningful and engaging. The assertion for conducting teaching and learning through ICT in teachers' training colleges is increasing day by day. There is no substitute for ICT in making the subject-matter meaningful, fascinating, and appreciable in a short period of time in the classroom environment. It continues to encourage the teachers and trainee-teachers to move beyond traditional education and embrace technology-based thinking and today they are constantly feeling the need for it.