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ZENODO
Article . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
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The Role of Small Intestinal Microbiota in Human Health and Disease: Current Understanding and Future Perspectives

Authors: Ojal Pratap Jadhav; Vaishali Choure;

The Role of Small Intestinal Microbiota in Human Health and Disease: Current Understanding and Future Perspectives

Abstract

The small intestine microbiota is becoming recognized as performing an important role in human health and illness. This review article investigates the composition and function of the small intestine microbiota, focusing on its role in digestion, nutritional absorption, immunological regulation, and pathogen protection. We investigated the link between microbial dysbiosis and a variety of gastrointestinal, metabolic, immune-mediated, and cognitive conditions. Therapeutic approaches such as probiotics, prebiotics, antibiotics, dietary changes, and fecal microbiota transplantation (FMT) are explored, with an emphasis on their effectiveness and safety. The paper also discusses the difficulties in investigating the small intestine microbiota, including methodological constraints and the necessity for tailored treatments. Future research directions are highlighted, with an emphasis on developing technologies and their ability to overcome current limits. This article emphasizes the significance of ongoing research to fully realize the therapeutic potential of the small intestine microbiota in clinical practice.

The small intestine microbiota is becoming recognized as performing an important role in human health and illness. This review article investigates the composition and function of the small intestine microbiota, focusing on its role in digestion, nutritional absorption, immunological regulation, and pathogen protection. We investigated the link between microbial dysbiosis and a variety of gastrointestinal, metabolic, immune-mediated, and cognitive conditions. Therapeutic approaches such as probiotics, prebiotics, antibiotics, dietary changes, and fecal microbiota transplantation (FMT) are explored, with an emphasis on their effectiveness and safety. The paper also discusses the difficulties in investigating the small intestine microbiota, including methodological constraints and the necessity for tailored treatments. Future research directions are highlighted, with an emphasis on developing technologies and their ability to overcome current limits. This article emphasizes the significance of ongoing research to fully realize the therapeutic potential of the small intestine microbiota in clinical practice.

Keywords

Small Intestine, Microbiota, Dysbiosis, Probiotics, Fecal Microbiota Transplantation, Metagenomics

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average