Economical effective complex fertilizers used for improving soil fertility can be produced in countries with suitable agricultural resources. The results of tests that were held on organo-mineral fertilizer, which consists of natural zeolite and brown coal of the Georgian origin are discussed in the article. The results obtained make it possible to consider the proposed substrate as an effective ameliorant providing long-term effect of the introduced fertilizer (prolongation effect), as well as preventing the washout of nutrients. The biometric indicators of plants grown on such a substrate are much higher than the control indexes. Further research in this direction will allow to change the technique of cultivation and upgrading of depleted grounds through the use of nanomaterials and substandard waste of the coal mining industry. Also it will improve the ecology of the environment and the quality of the final product.