AbstractAim: The aim of the present study to analyze the association between bone metabolic markers and CAD riskscore in the general population of Bihar region.Material & Methods: The present study was conducted at Department of Cardiology, Total 2000 participantswere included in the study.Results: There were 60% females and 40% males. Participants had co-morbidities like diabetes mellitus,dyslipidaemia, hypertension. The median Suita score was 43 points, and the median baPWV was 1,432 cm/s.TP1NP level was negatively associated with the CAD high-risk subgroup (Suita score ≥ 56) (odds ratio (OR) =0.78, 95% confidence interval (CI) = 0.69–0.82, P < 0.001). There were significant differences in age, sex,history of smoking, history of diabetes, history of CAD, body mass index (BMI), SBP, DBP, baPWV, Suitascore, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, creatinine, uric acid, corrected calcium,phosphorus, hemoglobin, hemoglobin A1c, and N-terminal fragment of pro-B-type natriuretic peptide (NTproBNP). Significant differences were observed in age, sex, smoking history, dyslipidemia history, hypertensionhistory, BMI, SBP, DBP, baPWV, Suita score, total cholesterol, tri- glyceride, HDL cholesterol, LDLcholesterol, creatinine, eGFR, uric acid, corrected calcium, phosphorus, hemoglobin, and hemoglobin A1c.Significant differences were observed in age, sex, smoking history, diabetes history, hypertension history, CADhistory, BMI, SBP, DBP, Suita score, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol,creatinine, uric acid, corrected calcium, phosphorus, hemoglobin, and hemoglobin A1c.Conclusion: This study demonstrated that TP1NP levels decreased in participants with high Suita scores andhigh baPWV, suggesting that TP1NP down regulation may indicate future CAD risk and atherosclerosisprogression in the general population of Bihar

AbstractAim: The aim of the present study to analyze the association between bone metabolic markers and CAD riskscore in the general population of Bihar region.Material & Methods: The present study was conducted at Department of Cardiology, Total 2000 participantswere included in the study.Results: There were 60% females and 40% males. Participants had co-morbidities like diabetes mellitus,dyslipidaemia, hypertension. The median Suita score was 43 points, and the median baPWV was 1,432 cm/s.TP1NP level was negatively associated with the CAD high-risk subgroup (Suita score ≥ 56) (odds ratio (OR) =0.78, 95% confidence interval (CI) = 0.69–0.82, P < 0.001). There were significant differences in age, sex,history of smoking, history of diabetes, history of CAD, body mass index (BMI), SBP, DBP, baPWV, Suitascore, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, creatinine, uric acid, corrected calcium,phosphorus, hemoglobin, hemoglobin A1c, and N-terminal fragment of pro-B-type natriuretic peptide (NTproBNP). Significant differences were observed in age, sex, smoking history, dyslipidemia history, hypertensionhistory, BMI, SBP, DBP, baPWV, Suita score, total cholesterol, tri- glyceride, HDL cholesterol, LDLcholesterol, creatinine, eGFR, uric acid, corrected calcium, phosphorus, hemoglobin, and hemoglobin A1c.Significant differences were observed in age, sex, smoking history, diabetes history, hypertension history, CADhistory, BMI, SBP, DBP, Suita score, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol,creatinine, uric acid, corrected calcium, phosphorus, hemoglobin, and hemoglobin A1c.Conclusion: This study demonstrated that TP1NP levels decreased in participants with high Suita scores andhigh baPWV, suggesting that TP1NP down regulation may indicate future CAD risk and atherosclerosisprogression in the general population of Bihar