Background: Coronary Artery Bypass Graft surgery (CABG) is one of the most common surgery procedures performed annually in worldwide. The objective of this study is to determine the prevalence and risk factors of the early neurologic complications emerged after CABG surgery. Materials and Methods: In a prospective study we have investigated 134 patients undergoing CABG between July 2016 and June 2017 in cardiac surgery ward, Bugshan hospital, Jeddah, KSA. Risk factors that evaluated in our analysis consist of hypertension (HTN), diabetes, body mass index (BMI), dyslipidemia and severity of carotid artery stenosis. Our dependent variables were change in conscious level, CVA and seizure. Results: In our analysis, of total 134 patients, 14 (10.4%) were female. Mean age of patients was 57?20 years. Of total patients, 72 (53.7%) were found to have HTN, 82 (61.2%) had diabetes, 110 (82.1%) had dyslipidemia, 6 (4.5%) significant (≥50%) carotid stenosis and 112 (83.6%) had abnormal [(≥25 kg/m?2) BMI, (40.3% were overweight (BMI ≥25 and ˂30 kg/m2), 35.8% obese (BMI ≥30 and ˂ 35 kg/m2) and 7.5% severely obese (BMI ≥35 kg/m2)]. The incidence rate of change in sensorium after CABG was 6 (4 was diagnosed as HIE and 2 with NCSE) and for CVA were 6 (4.5%). Dyslipidemia. BMI and HTN were the important risk factors. Conclusion: According to this analysis, Dyslipidemia, BMI and HTN were the most important risk factors of neurological complications after CABG.