Background: Neural axial blockade is the recommended type of anesthesia for lower limb procedures. Because of its quick onset, superior blockade, lower failure rates, and cost-effectiveness, spinal block is still the preferred treatment. The current study compares the effectiveness of intrathecal bupivacaine combined with buprenorphine and fentanyl in orthopaedic procedures involving the lower limbs. Method: Five patients were excluded because they did not meet the inclusion criteria out of 89 scheduled patients for lower abdomen and lower limb surgery. By using a computer-generated random number sequence, the remaining 84 patients were randomly split into two groups. The dosage for Group B was 50 μg of buprenorphine and 3 cc (15 mg) of strong Bupivacaine. Group F received 3cc (15mg) of Bupivacaine (heavy) and 25μg of fentanyl. Results: When combined with bupivacaine, buprenorphine, and fentanyl, spinal anesthesia offers high-quality intraoperative and postoperative analgesia. Sensory and motor blocks are greatly prolonged by buprenorphine and bupropion. Buprenorphine group has longer analgesia and sedation durations than Fentanyl group. Conclusion: Both groups’ hemodynamic stability was equivalent and statistically insignificant.

Background: Neural axial blockade is the recommended type of anesthesia for lower limb procedures. Because of its quick onset, superior blockade, lower failure rates, and cost-effectiveness, spinal block is still the preferred treatment. The current study compares the effectiveness of intrathecal bupivacaine combined with buprenorphine and fentanyl in orthopaedic procedures involving the lower limbs. Method: Five patients were excluded because they did not meet the inclusion criteria out of 89 scheduled patients for lower abdomen and lower limb surgery. By using a computer-generated random number sequence, the remaining 84 patients were randomly split into two groups. The dosage for Group B was 50 μg of buprenorphine and 3 cc (15 mg) of strong Bupivacaine. Group F received 3cc (15mg) of Bupivacaine (heavy) and 25μg of fentanyl. Results: When combined with bupivacaine, buprenorphine, and fentanyl, spinal anesthesia offers high-quality intraoperative and postoperative analgesia. Sensory and motor blocks are greatly prolonged by buprenorphine and bupropion. Buprenorphine group has longer analgesia and sedation durations than Fentanyl group. Conclusion: Both groups’ hemodynamic stability was equivalent and statistically insignificant.