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Thyroidal Hormonal Variations - A Neglected Entity in Type II Diabetes Mellitus

Authors: Bhagyamma Sollapurappa Narayanaswamy; Padmaja Pujari; Venkateswarulu. K.; Sreenivasulu Uppara; T Durga; P V Srinivasa Kumar;

Thyroidal Hormonal Variations - A Neglected Entity in Type II Diabetes Mellitus

Abstract

Introduction: The co-existence of thyroid dysfunction in type 2 diabetes mellitus patients will worsen the macrovascular and microvascular complications, morbidity, mortality, and quality of life. Over the years it has been evident that there exists regards a strong relationship between thyroid and diabetes. The incidence of thyroid diseases differs in different diabetic population. Thyroid through its hormones exert a great influence on various organs in the body. Similarly insulin also plays a major role in various cellular metabolic activities. Hence, a deficiency or excess of the thyroid hormones are thought to alter the functional integrity of insulin. Aim and Objective: The objective of this study was to determine the prevalence of thyroid dysfunction among patients with Type 2 diabetes. Methods: This Hospital based prospective cross sectional study was conducted from May 2022- May 2023. A total of 100 patients with type-2 diabetes who regularly attend the outpatient Endocrinology Department, GGH Ananthapuramu. A detailed history and examination was done after getting informed consent. Blood samples were collected and sent to the laboratory for the evaluation of thyroid profile. Results: Thyroid dysfunction was found in 36%of the patients with Type 2 DM. Among 100 patients the prevalence of subclinical hypothyroidism was 18 %, primary hypothyroidism was 10 %, clinical hyperthyroidism 16 %.and 64 are in euthyroid state. Conclusion: Thyroid Hormone testing is usually neglected in Type 2 Diabetes mellitus. Unidentified Thyroid Dysfunction will have impact on microvascular and macrovascular complications of Type 2DM. Thus, Routine Screening of Thyroid is advised in all patients of type 2 DM to reduce the morbidity and mortality.

Introduction: The co-existence of thyroid dysfunction in type 2 diabetes mellitus patients will worsen the macrovascular and microvascular complications, morbidity, mortality, and quality of life. Over the years it has been evident that there exists regards a strong relationship between thyroid and diabetes. The incidence of thyroid diseases differs in different diabetic population. Thyroid through its hormones exert a great influence on various organs in the body. Similarly insulin also plays a major role in various cellular metabolic activities. Hence, a deficiency or excess of the thyroid hormones are thought to alter the functional integrity of insulin. Aim and Objective: The objective of this study was to determine the prevalence of thyroid dysfunction among patients with Type 2 diabetes. Methods: This Hospital based prospective cross sectional study was conducted from May 2022- May 2023. A total of 100 patients with type-2 diabetes who regularly attend the outpatient Endocrinology Department, GGH Ananthapuramu. A detailed history and examination was done after getting informed consent. Blood samples were collected and sent to the laboratory for the evaluation of thyroid profile. Results: Thyroid dysfunction was found in 36%of the patients with Type 2 DM. Among 100 patients the prevalence of subclinical hypothyroidism was 18 %, primary hypothyroidism was 10 %, clinical hyperthyroidism 16 %.and 64 are in euthyroid state. Conclusion: Thyroid Hormone testing is usually neglected in Type 2 Diabetes mellitus. Unidentified Thyroid Dysfunction will have impact on microvascular and macrovascular complications of Type 2DM. Thus, Routine Screening of Thyroid is advised in all patients of type 2 DM to reduce the morbidity and mortality.

Keywords

Thyroid Dysfunction, Type 2 Diabetes Mellitus, Hyperthyroidism, Hypothyroidism, Thyroid Dysfunction, Type 2 Diabetes Mellitus, Hyperthyroidism, Hypothyroidism.

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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