Information Science is an interdisciplinary domain and plays a great role in the development at large. Information Science and Informatics normally treated as a synonym in academia worldwide. Information Science/Informatics is an applied science branch and thus with the combination of other areas and subject created many other knowledge cluster and field viz. Geo Information Science, Chemo Information Sciences, Environmental Information Science. Bio Information Sciences may be considered as a field of intersection of Biology and Information Science. Bio Informatics may be treated as one of the areas of Bio Information Sciences. Indian universities moving towards education, training, and research in interdisciplinary fields and as a result Bio related Informatics become vital. Higher Educational Institution’s number wise India also holds a rank in the world. In recent past private universities expanded rapidly. Many of them started offering Bio Informatics program in different level of study. This is a theoretical framework in terms of research paper and here several knowledge on information sciences, informatics with reference to Bio Informatics have been provided. The paper also highlighted emerging other allied areas including future potentialities in brief.