Backgrounds: One of the most prevalent causes of death among hospitalized patients in the critical care unit is sepsis (ICU). Because of the various co-morbidities and underlying disorders that these people have, diagnosing them is very difficult. A combination of hematological, biochemical, and microbiological tests can be used to identify sepsis. PCT and CRP levels are commonly considered valid indicators of the degree of systemic inflammation. The ratio of CRP to albumin is increasingly used as a biomarker for both systemic inflammation and nutritional status. The current study aimed to see if the CRP/albumin ratio, combined with procalcitonin, could be used to predict sepsis. Methods: This was a prospective cross-sectional study carried out with 150 patients. Baseline characteristics, biochemical investigations, and serum CRP/albumin ratios were done. The quantitative variables were expressed as mean and standard deviation compared by ANOVA followed by Bonferroni’s correction. A p-value of <0.05 was considered significant. Results: Serum procalcitonin levels were significantly higher on day-1 in non-survivors compared to survivors (P<0.0001). CRP/albumin ratio was substantially higher on day-1, day-3, and the day of discharge in non-survivors compared to survivors (P<0.0001). Conclusion: Despite the use of optimal treatment and an improved approach, the death rate in sepsis has been proven to be high (56.2 percent). Patients with increased procalcitonin and CRP/albumin ratio at admission can be better classified and identified as having a higher risk of adverse outcomes.

Backgrounds: One of the most prevalent causes of death among hospitalized patients in the critical care unit is sepsis (ICU). Because of the various co-morbidities and underlying disorders that these people have, diagnosing them is very difficult. A combination of hematological, biochemical, and microbiological tests can be used to identify sepsis. PCT and CRP levels are commonly considered valid indicators of the degree of systemic inflammation. The ratio of CRP to albumin is increasingly used as a biomarker for both systemic inflammation and nutritional status. The current study aimed to see if the CRP/albumin ratio, combined with procalcitonin, could be used to predict sepsis. Methods: This was a prospective cross-sectional study carried out with 150 patients. Baseline characteristics, biochemical investigations, and serum CRP/albumin ratios were done. The quantitative variables were expressed as mean and standard deviation compared by ANOVA followed by Bonferroni’s correction. A p-value of <0.05 was considered significant. Results: Serum procalcitonin levels were significantly higher on day-1 in non-survivors compared to survivors (P<0.0001). CRP/albumin ratio was substantially higher on day-1, day-3, and the day of discharge in non-survivors compared to survivors (P<0.0001). Conclusion: Despite the use of optimal treatment and an improved approach, the death rate in sepsis has been proven to be high (56.2 percent). Patients with increased procalcitonin and CRP/albumin ratio at admission can be better classified and identified as having a higher risk of adverse outcomes.