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ZENODO
Article . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
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Correlation of Atherogenic Index of Plasma with Coronary Artery Disease in Myocardial Infarction Patients: An Observational Study from NorthIndia

Authors: Gautam Jesrani; Dhananjay Singh Shekhawat; Gagan Mittal;

Correlation of Atherogenic Index of Plasma with Coronary Artery Disease in Myocardial Infarction Patients: An Observational Study from NorthIndia

Abstract

Background: Atherogenic Index of Plasma (AIP) is a newer marker of dyslipidemia that includes both atherogenic and anti-atherogenic lipid factors, i.e. triglycerides and high-density lipoprotein, and is recently studied for various cardio-vascular disease risk evaluations. However, its correlation with coronary artery disease (CAD) is scarcely described in the current literature. Aim: To study the correlation of AIP with CAD in myocardial infarction (MI) patients. Material and Methods: This was a single-centered observational study for a period of six months. Patients of age ≥18 years with a diagnosis of acute MI were included in this study, and lipid analysis was performed to identify the AIP. Then the patients underwent conventional CAG, and the GENSINI severity score was calculated on the basis of angiographic results. Both of these parameters were then correlated with Pearson’s ‘r’ correlation analysis and, a p-value <0.05 was considered statistically significant. Results: A total of 114 patients fulfilled the eligibility criteria and were included in this study. The mean age of the study group was 60.7 years, and male participants were more in numbers than female individuals (88 vs. 26). The average AIP and GENSINI scores were 0.15 and 35.8 respectively, and correlation analysis between the two parameters demonstrated a positive r-value (0.4405) with a statistically significant p-value. Conclusion: The study concluded that AIP has a positive correlation with CAD severity in the MI population.

Background: Atherogenic Index of Plasma (AIP) is a newer marker of dyslipidemia that includes both atherogenic and anti-atherogenic lipid factors, i.e. triglycerides and high-density lipoprotein, and is recently studied for various cardio-vascular disease risk evaluations. However, its correlation with coronary artery disease (CAD) is scarcely described in the current literature. Aim: To study the correlation of AIP with CAD in myocardial infarction (MI) patients. Material and Methods: This was a single-centered observational study for a period of six months. Patients of age ≥18 years with a diagnosis of acute MI were included in this study, and lipid analysis was performed to identify the AIP. Then the patients underwent conventional CAG, and the GENSINI severity score was calculated on the basis of angiographic results. Both of these parameters were then correlated with Pearson’s ‘r’ correlation analysis and, a p-value <0.05 was considered statistically significant. Results: A total of 114 patients fulfilled the eligibility criteria and were included in this study. The mean age of the study group was 60.7 years, and male participants were more in numbers than female individuals (88 vs. 26). The average AIP and GENSINI scores were 0.15 and 35.8 respectively, and correlation analysis between the two parameters demonstrated a positive r-value (0.4405) with a statistically significant p-value. Conclusion: The study concluded that AIP has a positive correlation with CAD severity in the MI population.

Keywords

Atherogenic index of plasma; Coronary angiography; Coronary artery disease; Dyslipidemia; Myocardial infarction

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average