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ZENODO
Article . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
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Formulation and Evaluation of Anti-Microbial Agent in Various Dosage Forms by Using Ethnopharmacological Selected Indian Medicinal Plants (Solanum xanthocarpum, Adhatoda vasica nees, Oscimum sanctum)

Authors: Chandrachud Sharma; Yuvraj Singh Sarangdevot;

Formulation and Evaluation of Anti-Microbial Agent in Various Dosage Forms by Using Ethnopharmacological Selected Indian Medicinal Plants (Solanum xanthocarpum, Adhatoda vasica nees, Oscimum sanctum)

Abstract

The foundation of the herbal medication business is the ethnomedical values of plants. In order to create herbalmedications with minimal side effects, India has contributed its expertise in traditional system medicines(Ayurveda and Siddha). These plants have historically been utilised by tribal communities in India as extracts,powders, or pastes to cure conditions including anti-microbial activity, cough and colds, fever, stomach, kidney,and liver diseases, pain, inflammation, and wounds. The current study focuses on the antibacterial properties ofIndian medicinal herbs such Ocimum sanctum, Adhatoda vasica, and Solanum xanthocarpum. Numerous of thelong-standing ethnomedicinal applications of these plants are supported by ethnopharmacological investigations.These three ethnomedicinal plants have yielded several phytoconstituents, some of which have exhibitedpharmacological activity through in vivo and/or in vitro tests. For herbal medicines to be used safely andeffectively, ethnomedical applications that are backed by scientific research are crucial. Using the agar-welldiffusion method and various concentrations (30%, 50%, 70%, and 100%), the antibacterial activity of theSolanaceae family plant Solanum xanthocarpum was assessed in vitro against a number of human pathogenicmicroorganisms, including Escherichia coli, Yersinia pestis, Pseudomonas aeruginosa, and Staphylococcusaureus. In comparison to the control group, chicken flesh that had been washed with AVELE for 90 minutes hadhigher sensory attribute ratings for juice and tenderness as well as a higher overall sensory quality. This studydemonstrates AVELE's ability to kill L. monocytogenes NCIM 24563 effectively, indicating that it may beutilised as a marinade or rinse for meat preservation. The Lamiaceae family of plants includes the fragrant herbOcimum sanctum Linn, sometimes known as holy basil. It is a native of the tropics of Asia and Africa. Toprepare the leaves for grinding, they were detached from the stem, thoroughly cleaned in clear water, and thendried for seven days. In order to create a uniform powder, dried leaves were ground separately in an electricgrinder. The powder produced using the "cold extraction method" was converted into ethanol, hexane, andchloroform extract. Ocimum sanctum leaves' antibacterial effectiveness suggests that the plant has strongantimicrobial qualities. Additionally, because ocimum is so common in India, it might be suggested as aconveniently accessible source of antibacterial compounds in place of synthetic chemicals

The foundation of the herbal medication business is the ethnomedical values of plants. In order to create herbalmedications with minimal side effects, India has contributed its expertise in traditional system medicines(Ayurveda and Siddha). These plants have historically been utilised by tribal communities in India as extracts,powders, or pastes to cure conditions including anti-microbial activity, cough and colds, fever, stomach, kidney,and liver diseases, pain, inflammation, and wounds. The current study focuses on the antibacterial properties ofIndian medicinal herbs such Ocimum sanctum, Adhatoda vasica, and Solanum xanthocarpum. Numerous of thelong-standing ethnomedicinal applications of these plants are supported by ethnopharmacological investigations.These three ethnomedicinal plants have yielded several phytoconstituents, some of which have exhibitedpharmacological activity through in vivo and/or in vitro tests. For herbal medicines to be used safely andeffectively, ethnomedical applications that are backed by scientific research are crucial. Using the agar-welldiffusion method and various concentrations (30%, 50%, 70%, and 100%), the antibacterial activity of theSolanaceae family plant Solanum xanthocarpum was assessed in vitro against a number of human pathogenicmicroorganisms, including Escherichia coli, Yersinia pestis, Pseudomonas aeruginosa, and Staphylococcusaureus. In comparison to the control group, chicken flesh that had been washed with AVELE for 90 minutes hadhigher sensory attribute ratings for juice and tenderness as well as a higher overall sensory quality. This studydemonstrates AVELE's ability to kill L. monocytogenes NCIM 24563 effectively, indicating that it may beutilised as a marinade or rinse for meat preservation. The Lamiaceae family of plants includes the fragrant herbOcimum sanctum Linn, sometimes known as holy basil. It is a native of the tropics of Asia and Africa. Toprepare the leaves for grinding, they were detached from the stem, thoroughly cleaned in clear water, and thendried for seven days. In order to create a uniform powder, dried leaves were ground separately in an electricgrinder. The powder produced using the "cold extraction method" was converted into ethanol, hexane, andchloroform extract. Ocimum sanctum leaves' antibacterial effectiveness suggests that the plant has strongantimicrobial qualities. Additionally, because ocimum is so common in India, it might be suggested as aconveniently accessible source of antibacterial compounds in place of synthetic chemicals

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Keywords

Ethnomedicinal plants, Solanum xanthocarpum, Adhatoda vasica, Ocimumsanctum, Antimicrobial, Staphylococcus aureus,Phytoconstituents

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average