Introduction and Objective: Polycystic Ovarian Syndrome also called as PCOS or PCOD (Polycystic Ovarian Disorder) This disorder is an endocrinopathy, and that’s why it should be referred to as PCOS, a syndrome rather than a disease. Amenorrhoea, weight gain, hirsutism, diabetes mellitus, hypertension, cardiovascular disease, cerebrovascular disease, breastmilk expression in absence of pregnancy and infertility are some of the clinical manifestations caused by PCOS. The objective of this study was to observe the various hormonal and biochemical factors that influence PCOS in the Barak valley region of Assam. Methodology: A total number of 20 cases of reproductive age group of 18-38 yrs were selected for the study fulfilling the following criteria’s: USG > 12 antral follicles and clinical complaints and findings with anovulation and hyperandrogenism Glucose estimation was done by GOD POD (glucose oxidase peroxidase). The tests were carried out in semiautomated biochemistry analyser (ERBA Transasia) HBA1c estimation was done by Turbodyne SC Tulip and hormonal analysis was done by Classic radiance semiautomated CLIA plate analyser. Free testosterone was done from outsource. Results: 7 cases are hypogonadotrophic and 13 cases are normogonadotrophic subjects who presented with polycystic ovaries. High TSH was found in 15.4% high LH/FSH ratio in 61.5% high prolactin in 69.2%, low prolactin in 15.4% high AMH in 84.6% and high insulin in 30.8% of cases The status of ANOVA shows a significant p value of <0.05 for LH and insulin. High AMH and high LH/FSH ratio were responsible for PCOS. Conclusion: Hormonal abnormalities hamper the normal folliculogenesis, hence needs corelation and correction.

Introduction and Objective: Polycystic Ovarian Syndrome also called as PCOS or PCOD (Polycystic Ovarian Disorder) This disorder is an endocrinopathy, and that’s why it should be referred to as PCOS, a syndrome rather than a disease. Amenorrhoea, weight gain, hirsutism, diabetes mellitus, hypertension, cardiovascular disease, cerebrovascular disease, breastmilk expression in absence of pregnancy and infertility are some of the clinical manifestations caused by PCOS. The objective of this study was to observe the various hormonal and biochemical factors that influence PCOS in the Barak valley region of Assam. Methodology: A total number of 20 cases of reproductive age group of 18-38 yrs were selected for the study fulfilling the following criteria’s: USG > 12 antral follicles and clinical complaints and findings with anovulation and hyperandrogenism Glucose estimation was done by GOD POD (glucose oxidase peroxidase). The tests were carried out in semiautomated biochemistry analyser (ERBA Transasia) HBA1c estimation was done by Turbodyne SC Tulip and hormonal analysis was done by Classic radiance semiautomated CLIA plate analyser. Free testosterone was done from outsource. Results: 7 cases are hypogonadotrophic and 13 cases are normogonadotrophic subjects who presented with polycystic ovaries. High TSH was found in 15.4% high LH/FSH ratio in 61.5% high prolactin in 69.2%, low prolactin in 15.4% high AMH in 84.6% and high insulin in 30.8% of cases The status of ANOVA shows a significant p value of <0.05 for LH and insulin. High AMH and high LH/FSH ratio were responsible for PCOS. Conclusion: Hormonal abnormalities hamper the normal folliculogenesis, hence needs corelation and correction.