Aim: The aim of the present study was to assess the clinical significance of serum uric acid, serum calcium, serumcreatinine and serum electrolytes in patients with kidney stone.Methods: The present study was conducted in the Department of Surgery and 200 patients were included in thestudy. The patients were divided into two groups according to serum UA levels: the UA-high group withhyperuricemia (serum UA ≥ 7.0 mg/dL) or the UA-low group with normal UA levels (serum UA < 7.0 mg/dL)groups.Results: Patient background was significantly different between the UA stone patients and the patients withCoax/CaP stones in age, sex, body mass index, HTN, DM, CVD, hemoglobin, serum Alb, serum UA,hyperuricemia, triglyceride, and stage 3 CKD. The UA-low group comprised 50 control subjects and pair-matched25 patients with UA stones. There were no statistically significant differences in background between UA stonepatients and control subjects. The UA-high group comprised 10 patients with UA stones and 20 pair-matchedcontrol subjects. There were no statistically significant differences in background between UA stone patients andcontrol subjects. The UA-low group comprised pair-matched 20 patients with CaOx/CaP and 20 patients with UAstones. There were no statistically significant differences in background between UA stone patients and CaOx/CaPpatients. The UA-high group comprised 10 patients with CaOx/CaP and pair-matched 10 patients with UA stones.There were no statistically significant differences in background between UA stone patients and control subjects.Conclusion: Patients with UA stones had significantly worse renal function than controls and CaOx/CaP patientsregardless of hyperuricemia. Urolithiasis (CaOx/CaP and UA stone) and hyperuricemia had an association withimpaired renal function. Our findings encourage clinicians to initiate intensive treatment and education approachesin patients with urolithiasis and/or hyperuricemia in order to prevent the progression of renal impairment.

Aim: The aim of the present study was to assess the clinical significance of serum uric acid, serum calcium, serumcreatinine and serum electrolytes in patients with kidney stone.Methods: The present study was conducted in the Department of Surgery and 200 patients were included in thestudy. The patients were divided into two groups according to serum UA levels: the UA-high group withhyperuricemia (serum UA ≥ 7.0 mg/dL) or the UA-low group with normal UA levels (serum UA < 7.0 mg/dL)groups.Results: Patient background was significantly different between the UA stone patients and the patients withCoax/CaP stones in age, sex, body mass index, HTN, DM, CVD, hemoglobin, serum Alb, serum UA,hyperuricemia, triglyceride, and stage 3 CKD. The UA-low group comprised 50 control subjects and pair-matched25 patients with UA stones. There were no statistically significant differences in background between UA stonepatients and control subjects. The UA-high group comprised 10 patients with UA stones and 20 pair-matchedcontrol subjects. There were no statistically significant differences in background between UA stone patients andcontrol subjects. The UA-low group comprised pair-matched 20 patients with CaOx/CaP and 20 patients with UAstones. There were no statistically significant differences in background between UA stone patients and CaOx/CaPpatients. The UA-high group comprised 10 patients with CaOx/CaP and pair-matched 10 patients with UA stones.There were no statistically significant differences in background between UA stone patients and control subjects.Conclusion: Patients with UA stones had significantly worse renal function than controls and CaOx/CaP patientsregardless of hyperuricemia. Urolithiasis (CaOx/CaP and UA stone) and hyperuricemia had an association withimpaired renal function. Our findings encourage clinicians to initiate intensive treatment and education approachesin patients with urolithiasis and/or hyperuricemia in order to prevent the progression of renal impairment.