African American college students have among the highest levels of sexual activity, yet many African American college students are lacking knowledge and confidence in making informed decisions before engaging in a sexual activity. Previous studies noted that risky sexual behavior among college students and young adults remains a public health concern given the high percentage of unintended pregnancies in the U.S. and sexually transmitted diseases. The purpose of the research is to examine the sexual attitudes, behaviors, and beliefs of African American college men and women attending a higher education institution in a rural setting and understand what factors have impacted African American college students’ sexual attitudes, behaviors, and beliefs. The researchers offer recommendations on how to engage and empower African American college students so that they can be more knowledgeable and confident in making informed decisions with their sexual attitudes, behaviors, and beliefs.