The EOSC4Cancer initiative addresses the pressing need for advanced research and infrastructure in tackling cancer, particularly in Europe. This document focuses on the WP5 initiative within EOSC4Cancer, which aims to empower clinicians and cancer researchers through capacity building. Emphasizing the importance of tailored training, the document outlines the design process for learning paths, including short-term courses and traditional postgraduate options. Key concepts such as learning outcomes and FAIR training are introduced, and the systematic mapping of skills and roles within the target audience is detailed. Illustrative examples from both within and beyond the project demonstrate the application of these principles. The document concludes with a list of practical tools and services for constructing effective learning paths. Importantly, this document is a living resource, reflecting ongoing efforts and intended to contribute to a dynamic learning environment beyond the EOSC4Cancer project, benefiting the broader scientific community.