(9) April 2023 | Volume 1 | Issue 2 Abstract Background: Autism is a neurodevelopmental disorder with impairment in social emotional and communication domains and presence of repetitive behaviours and restrictive interest. Social communication disorder is closely related to Autism and is characterized by a persistent difficult y i n usin g verba l an d nonverbal communication in a socially appropriate manner with absence of stereotypical behaviour present in autism. Excessive screen time has significant impact on the quality of life of children especially those with neurodevelopmental disorders like autism, SCD.Quality of life evaluation has a significant influenc e o n th e treatmen t and intervention options of ASD children. Hence, this study was conducted to compare the effect of screentime in quality of life of children with autism and SCD. Methods: 60 children in the age group of 2-10 years diagnosed with ASD/SCD along with 60 age and sex matched normal children as controls were included in the study. After applying exclusion criteria, informed consent, detailed history including complete details of screen exposure was obtained and evaluation was done. Pediatric Quality of life inventory (PedsQL) was used to assess the quality of life of these children.Data were analysed and comparison was done using SPSS-23 statistical software. Results: In the study,8 girls and 20 boys were diagnosed with SCD and 10 girls and 22 boys were diagnosed with ASD.65% of children were in 2-5 years of age and 35 % were in 5-10 year age group. Children with ASD with screen time 2hrs was 40.7% and in SCD, screen time 2 hours was 17.8%. 8(72.7%) children with severe ASD had screen time >2 hours while only 1 child with severe SCD had screen time >2 hours.The quality of life was significantly different between the control and the ASD/SCD groups with ASD group more significantly affected . Further , the difference in quality of life was statistically significant with ASD and SCD having higher screen exposure, with ASD children more affected (p value < 0.01%) Conclusion: Quality of life is affected in children with ASD and SCD, but more so in ASD children with screen exposure. Hence parents must strictly adhere to the screen time guidelines of Indian Academy of Pediatrics to improve the overall prognosis INDIAN JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS (10) April 2023 | Volume 1 | Issue 2 Aadarsh Pvt. Ltd. and quality of life in children with autism and SCD, which in turn may have significant effect on effectivenes s o f therapy. Whil e giving therapy with electronic tools in children with communication disorders, specific caution on quality of program should be considered for the ASD subgroups than in SCD