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Towards systematically assessing bioactivity of natural compounds or bio-ligands: Cannabidiol as an example

Authors: Bomi Joseph; Donish Cushing;

Towards systematically assessing bioactivity of natural compounds or bio-ligands: Cannabidiol as an example

Abstract

It is estimated that 75-78% of all modern medicines are directly or indirectly derived from higher plants. Less than 5% of all plant species have been explored for their medical potential. Natural plant compounds rarely have side effects. This makes them a potent alternative to pharmaceutical drugs for chronic use. All active ingredients from plants are biological molecules. They have a complex biochemical pathway to produce a somatic effect on the human body. In order for plant materials to rival pharmaceutical drugs, they have to undergo the same pharmaceutical factors – namely measurement of its bioactivity, knowledge of its pharmacokinetic and pharmacodynamic properties, and standardized quantities of active ingredient with the indential bioactive properties.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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