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An association between osteoarthritis (OA) and functional polymorphisms in the aspartic acid (D) repeat of the asporin (ASPN) gene was reported in Japanese and Han Chinese populations. The aim of this study was to assess the association of variants in the ASPN gene with the presence of radiographic hand and/or knee OA in a US Caucasian population.
Male, Genotype, Knee Joint, Hand Joints, Statistics as Topic, Biomedical Engineering, White People, Rheumatology, Osteoarthritis, Genetics, Humans, Knee, Orthopedics and Sports Medicine, Genetic Predisposition to Disease, Polymorphism, Taxonomy, Asporin, Aged, Aspartic Acid, Extracellular Matrix Proteins, Polymorphism, Genetic, Siblings, Biodiversity, Middle Aged, Hand, United States, Pedigree, Female
Male, Genotype, Knee Joint, Hand Joints, Statistics as Topic, Biomedical Engineering, White People, Rheumatology, Osteoarthritis, Genetics, Humans, Knee, Orthopedics and Sports Medicine, Genetic Predisposition to Disease, Polymorphism, Taxonomy, Asporin, Aged, Aspartic Acid, Extracellular Matrix Proteins, Polymorphism, Genetic, Siblings, Biodiversity, Middle Aged, Hand, United States, Pedigree, Female
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