Clinopodium nepeta is reported for the first time from Mexico as a naturalized plant based on two populations located in Oaxaca and San Luis Potosí. This is a variable species broadly cultivated in several countries as culinary, medicinal and ornamental plant. However, it has not been extensively grown in Mexico. We present a description of the species in the country in order to facilitate its identification and avoid possible confusion with native species of Clinopodium or Hedeoma.