A new species of Metrodorea (Rutaceae), M. concinna, is described and illustrated, and morphological, molecular phylogenetic, and distributional support for the new taxon and its relationships with morphologically similar species, as well as with sympatric ones, are explored. The new species is endemic to semideciduous forests of southeastern Bahia, eastern Brazil. It is distinct from other species of the genus mainly by the combination of shrubby to treelet habit, (sub)sessile leaves, sessile leaflets without conspicuous, dark glands on the abaxial surface, and by each carpel bearing one dorsal apophysis. In addition to the diagnostic morphological features, molecular data provide further support to the new taxon.