Due to increase in energy prices at peak periods and increase in fuel cost, involving Distributed Generation (DG) and consumption management by Demand Response (DR) will be unavoidable options for optimal system operations. Also, with high penetration of DGs and DR programs into power system operation, the reliability criterion is taken into account as one of the most important concerns of system operators in management of power system. In this paper, a Reliability Constrained Unit Commitment (RCUC) at presence of time-based DR program and DGs integrated with conventional units is proposed and executed to reach a reliable and economic operation. Designated cost function has been minimized considering reliability constraint in prevailing UC formulation. The UC scheduling is accomplished in short-term so that the reliability is maintained in acceptable level. Because of complex nature of RCUC problem and full AC load flow constraints, the hybrid algorithm included Simulated Annealing (SA) and Binary Particle Swarm Optimization (BPSO) has been proposed to optimize the problem. Numerical results demonstrate the effectiveness of the proposed method and considerable efficacy of the time-based DR program in reducing operational costs by implementing it on IEEE-RTS79.