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Iron salt-promoted oxidation of steroidal phenols by m-chloroperbenzoic acid: a route to possible antitumor agents

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2022 Serbia English Publisher:Royal Society of Chemistry (RSC)Journal:RSC Advances, volume 12, pages 20,649-20,655 (eissn: 2046-2069, Copyright policy )Funded by:MESTD | Ministry of Education, Sc..., MESTD | Ministry of Education, Sc...
Authors: Kop Tatjana J; Terzić-Jovanović Nataša; Žižak Željko; Šolaja Bogdan A; Milić Dragana R;

doi: 10.1039/d2ra03717c

pmid: 35919136

pmc: PMC9290445

Iron salt-promoted oxidation of steroidal phenols by m-chloroperbenzoic acid: a route to possible antitumor agents

Abstract

Iron salt-promoted reaction of estrone and its derivatives with meta-chloroperoxybenzoic acid was developed and epoxyquinols were further transformed. Most compounds showed in vitro antiproliferative activity.

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Serbia
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Keywords

antiproliferative activity, Chemistry, Fe(ii)/Fe(iii)-MCPBA system, biologically active natural products, EPR, m-chloroperoxybenzoic acid (MCPBA), p-quinol

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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