Three Lycopodium alkaloids from Thai club mosses
Copyright policy )Three Lycopodium alkaloids from Thai club mosses
Phytochemical constituents in alkaloid extracts from three Thai club mosses Huperzia squarrosa, Huperzia phlegmaria and Phlegmariurus nummularifolius were investigated. Squarrosinoxide was an undescribed Lycopodium alkaloid from H. squarrosa possessing an unprecedented 6/5/7 tricyclic spiro system. Acetyllycophlegmarianol was an undescribed N-oxide lycopodine-type alkaloid isolated from H. phlegmaria. 4-Epilycopodine, an undescribed epimer of lycopodine, was first isolated from P. nummularifolius. The structural assignments were established through comprehensive spectroscopic techniques and chemical correlations. All compounds were assayed for their anti-acetylcholinesterase activity in vitro.
- Chulabhorn Research Institute Thailand
- Chulabhorn Graduate Institute Thailand
- Commission on Higher Education Philippines
- Chulabhorn Royal Academy Thailand
- Office of the Higher Education Commission Thailand
Molecular Conformation, Biodiversity, Thailand, Lycopodium, Alkaloids, Electrophorus, Acetylcholinesterase, Animals, Lycopodiaceae, Cholinesterase Inhibitors, Taxonomy
Molecular Conformation, Biodiversity, Thailand, Lycopodium, Alkaloids, Electrophorus, Acetylcholinesterase, Animals, Lycopodiaceae, Cholinesterase Inhibitors, Taxonomy
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