In this paper we show that the concept of maximal $L^p$-regularity is stable under a large class of unbounded perturbations, namely Staffans-Weiss perturbations. To that purpose, we first prove that the analyticity of semigroups is preserved under this class of perturbations, which is a necessary condition for the maximal regularity. In UMD spaces, $\mathcal{R}$-boundedness conditions are exploited to give conditions guaranteing the maximal regularity. For non-reflexive Banach space, a condition is imposed to the Dirichlet operator associated to the boundary value problem to prove the maximal regularity. A Pde example illustrating the theory and an application to a class of non-autonomous perturbed boundary value problems are presented.

24 pages. arXiv admin note: substantial text overlap with arXiv:1810.08964