Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of west Siberia
Copyright policy )Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of west Siberia
Based on population analysis of the DRB1, DQA1, DQB1 and TNFA allele frequency distribution patterns, regional features of immunogenetic structure of the population of West Siberia were investigated. Statistically significant linkage disequilibrium within the HLA class II region, as well as between the TNFA and DRB1, DQA1, and DQB1 was demonstrated. Population frequency distribution patterns of two- and multilocus haplotypes were examined.
- Research Institute of Medical Problems of the North Russian Federation
- Institute of Clinical and Experimental Lymphology Russian Federation
- Russian Academy of Sciences Russian Federation
- Russian Academy
Male, Tumor Necrosis Factor-alpha, HLA-DR Antigens, Emigration and Immigration, Moscow, HLA-DQ alpha-Chains, Linkage Disequilibrium, Siberia, Gene Frequency, Haplotypes, HLA-DQ Antigens, HLA-DQ beta-Chains, Humans, Female, Alleles, HLA-DRB1 Chains
Male, Tumor Necrosis Factor-alpha, HLA-DR Antigens, Emigration and Immigration, Moscow, HLA-DQ alpha-Chains, Linkage Disequilibrium, Siberia, Gene Frequency, Haplotypes, HLA-DQ Antigens, HLA-DQ beta-Chains, Humans, Female, Alleles, HLA-DRB1 Chains
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