In order to accomplish the Prognostics and Health Management System(PHM) for guided missile, sensor network node of storage and conveyance’s environment’s monitoring based on multi-MEMS sensors is designed. Centering on the low power consumption singlechip, microsensor collecting the information of temperature, humidity, acceleration(calculate quiver), and magnetic field intensity(calculate posture), realizing the wireless communication between the node and the upper management system (ARM controller) with the radio frequency send-receive chip nRF2401. This node has the characteristic of small volume, easy to layout, low power consumption, continuous operation for long time and so on. It preferably realized the function of information terminal of PHM system.