The Tinkerbell (Tink) Mutation Identifies the Dual-Specificity MAPK Phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) as a Novel Regulator of Organ Size in Arabidopsis
Copyright policy )The Tinkerbell (Tink) Mutation Identifies the Dual-Specificity MAPK Phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) as a Novel Regulator of Organ Size in Arabidopsis
Mitogen-activated dual-specificity MAPK phosphatases are important negative regulators in the MAPK signalling pathways responsible for many essential processes in plants. In a screen for mutants with reduced organ size we have identified a mutation in the active site of the dual-specificity MAPK phosphatase indole-3-butyric acid-response5 (IBR5) that we named tinkerbell (tink) due to its small size. Analysis of the tink mutant indicates that IBR5 acts as a novel regulator of organ size that changes the rate of growth in petals and leaves. Organ size and shape regulation by IBR5 acts independently of the KLU growth-regulatory pathway. Microarray analysis of tink/ibr5-6 mutants identified a likely role for this phosphatase in male gametophyte development. We show that IBR5 may influence the size and shape of petals through auxin and TCP growth regulatory pathways.
- John Innes Centre United Kingdom
- University of Potsdam Germany
- Nara Institute of Science and Technology Japan
- Sainsbury Laboratory United Kingdom
- Universitat Politècnica de València Spain
ddc:500, Science, Molecular Sequence Data, Arabidopsis, 610, Genes, Recessive, Flowers, Cytochrome P-450 Enzyme System, Gene Expression Regulation, Plant, Amino Acid Sequence, Institut für Biochemie und Biologie, Conserved Sequence, ddc:610, Indoleacetic Acids, Sequence Homology, Amino Acid, Arabidopsis Proteins, Q, R, 500, Organ Size, Microarray Analysis, Plant Leaves, Mutation, Medicine, Dual-Specificity Phosphatases, Pollen, Mathematisch-Naturwissenschaftliche Fakultät, Cell Division, Research Article, Signal Transduction, Transcription Factors
ddc:500, Science, Molecular Sequence Data, Arabidopsis, 610, Genes, Recessive, Flowers, Cytochrome P-450 Enzyme System, Gene Expression Regulation, Plant, Amino Acid Sequence, Institut für Biochemie und Biologie, Conserved Sequence, ddc:610, Indoleacetic Acids, Sequence Homology, Amino Acid, Arabidopsis Proteins, Q, R, 500, Organ Size, Microarray Analysis, Plant Leaves, Mutation, Medicine, Dual-Specificity Phosphatases, Pollen, Mathematisch-Naturwissenschaftliche Fakultät, Cell Division, Research Article, Signal Transduction, Transcription Factors
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