Abstract To assess the effectiveness of probiotic preparation “Enzymsporin” together with grass meal, green mass of Jerusalem artichoke, when fattening young rabbits, matched 180 rabbits (males) of “Hypharm” French breeding in conditions of the industrial complex of LLC “Lipetsk rabbit” which at the age of 45 days were divided into 3 groups on the principle of the groups – analogues. Fattening was carried out until the age of 105 days. Rabbits of the 1st group (control) received all-mash without additives. The rabbits in group 2 and group 3 were fed with the probiotic preparation “Enzymsporin” in a dosage of 0.6 g/kg of all-mash (rabbits of the 2nd group) and 1.0 g/kg of all-mash (rabbits of the 3rd group) together with grass meal, green mass of Jerusalem artichoke in a dose of 15.0% by weight of all-mash. At the age of 105 days, the rabbits of the 1st group (control) were characterized by live weight, which was less than the mass of animals of the 1st experimental group by 189.0 g, or by 5.95 %, the 2nd experimental group - by 367.0 g, or 11.55 %. Thus, the preparation “Enzymsporin” together with grass meal, green mass of the Jerusalem artichoke is a promising product from a number of probiotics used in animal nutrition and allows improving the productivity and meat quality of rabbits.