Among the various electricity consumer sectors, the consumption level of the industrial sector is often considered as the largest portion of electricity consumption, highlighting the urgent need to implement demand response (DR) energy management. However, implementation of DR for the industrial sector requires a more sophisticated and different scheme compared to the residential and commercial sector. This study explores all the elastic segments of plant multi‐energy production, conversion, and consumption. We then construct a real‐time industrial facilities management problem as an optimal dispatch model to enclose these elastic segments and production constraints in cyber‐physical environments. Moreover, a model predictive‐based centralised dispatch scheme is proposed to address the uncertainties of real‐time price and renewable energy forecasting while considering the sequence of the production process. Numerical results demonstrate that the proposed scheme can enhance energy efficiency and economics of lithium battery manufacturing plant through responding to the real‐time price whilst ensuring the completion of production tasks.