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Planta Medica
Article . 1995 . Peer-reviewed
Data sources: Crossref
Planta Medica
Article . 1995
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An Antifungal Naphthoquinone, Xanthones and Secoiridoids fromSwertia calycina

Authors: Rodriguez, S; Wolfender, Jean-Luc; Hakizamungu, E; Hostettmann, K;

An Antifungal Naphthoquinone, Xanthones and Secoiridoids fromSwertia calycina

Abstract

A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.

Country
Switzerland
Related Organizations
Keywords

Antifungal Agents/isolation & purification/pharmacology, Antifungal Agents, Plant Extracts, Iridoid Glucosides, Rwanda, Microbial Sensitivity Tests, Glucosides/isolation & purification/pharmacology, Mass Spectrometry, Pyrans/isolation & purification/pharmacology, Naphthoquinones/isolation & purification/pharmacology, Glucosides, Iridoids, Chromatography, High Pressure Liquid, Naphthoquinones, Pyrans

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    53
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
53
Top 10%
Top 10%
Top 10%
Green