Three new species of Eriogonum have been identified from field research and ongoing molecular systematic analysis of selected members of Eriogonum subg. Eucycla. Eriogonum alexanderae, formerly recognized as a variety of E. ochrocephalum or subsumed within E. crosbyae, warrants species-level designation. Eriogonum calcareum, also previously recognized as a variety of E. ochrocephalum, shares many affinities with the narrowly distributed E. novonudum, however range and morphology do not overlap between these two species. Eriogonum crosbyae var. mystrium shares a more similar evolutionary history to E. crosbyae, rather than E. prociduum, thus a new combination is proposed. Eriogonum domitum is described as a new species. This isolated taxon from west-central Utah is no longer thought to be a member of E. mancum, differing in morphological characters, geographic distribution and molecular information.