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Robust inference of positive selection on regulatory sequences in the human brain

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type , Preprint 11 Mar 2020 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Advances, volume 6 (eissn: 2375-2548,

Authors: Marc Robinson-Rechavi; Marc Robinson-Rechavi; Jialin Liu; Jialin Liu;

doi: 10.1126/sciadv.abc9863 , 10.1101/2020.03.09.984047

pmid: 33246961

pmc: PMC7695467

Robust inference of positive selection on regulatory sequences in the human brain

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Abstract

A new method provides evidence that evolution of gene activity in the human brain was driven by natural selection.

Related Organizations

Department of Ecology and Evolution
Switzerland
University of Basel
Switzerland
University of Lausanne
Switzerland
SIB Swiss Institute of Bioinformatics
Switzerland
University of Lausanne
Switzerland

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Keywords

Binding Sites, Pan troglodytes, Brain, Regulatory Sequences, Nucleic Acid, Evolution, Molecular, Mice, Animals, Humans, Selection, Genetic, Research Articles, Transcription Factors

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	22
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