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Pseudonocardia antitumoralis sp. nov., a deoxynyboquinone-producing actinomycete isolated from a deep-sea sediment

Authors: Xin-Peng, Tian; Li-Juan, Long; Su-Mei, Li; Jing, Zhang; Ying, Xu; Jie, He; Jie, Li; +4 Authors

Pseudonocardia antitumoralis sp. nov., a deoxynyboquinone-producing actinomycete isolated from a deep-sea sediment

Abstract

An aerobic actinomycete, designated SCSIO 01299T, was isolated from a deep-sea sediment collected from the northern South China Sea at a depth of 3258 m. The isolate was found to be a natural producer of the synthesized antitumour agent deoxynyboquinone and its three new derivatives, pseudonocardians A, B and C. A blast search based on almost-complete 16S rRNA gene sequences showed that strain SCSIO 01299T had high sequence similarities with members of the genus Pseudonocardia . The 16S rRNA gene sequence phylogenetic tree revealed that strain SCSIO 01299T was a member of the genus Pseudonocardia . Phenotypic analysis, chemotaxonomy and DNA–DNA relatedness could readily distinguish the isolate from established members in this genus. It was concluded that strain SCSIO 01299T represents a novel species, for which the name Pseudonocardia antitumoralis sp. nov. is proposed. The type strain is SCSIO 01299T ( = DSM 45322T = CCTCC M 2011255T).

Related Organizations
Keywords

DNA, Bacterial, China, Geologic Sediments, Fatty Acids, Molecular Sequence Data, Quinones, Nucleic Acid Hybridization, Vitamin K 2, Sequence Analysis, DNA, Bacterial Typing Techniques, RNA, Ribosomal, 16S, Actinomycetales, Seawater, Water Microbiology, Phylogeny

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
32
Top 10%
Top 10%
Top 10%
hybrid