Histiocytic disorders of children and adults: introduction to the problem, overview, historical perspective and epidemiology

Name: Histiocytic disorders of children and adults: introduction to the problem, overview, historical perspective and epidemiology
Keywords: 3. Good health

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 19 May 2005Publisher:Cambridge University Press (CUP)

Authors: Sheila Weitzman; R. Maarten Egeler;

doi: 10.1017/cbo9780511545252.002

Histiocytic disorders of children and adults: introduction to the problem, overview, historical perspective and epidemiology

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Abstract

The histiocytic disorders are defined as disorders due to an abnormal accumulation of cells of the mononuclear phagocytic system (MPS), consisting of dendritic cells (DCs) and macrophages. They comprise a wide variety of diverse conditions that affect both children and adults, and have been difficult to classify and to treat. Figure 1.1 is a simplified schematic representation of the development of various components of the MPS from the primitive CD34 hematopoietic stem cell. 1

Related Organizations

University of Toronto
Canada
Leiden University
Netherlands

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