Genetics of Sex Determination in Tilapiine Species
Copyright policy )Genetics of Sex Determination in Tilapiine Species
We identified DNA markers linked to sex determining genes in six closely related species of tilapiine fishes. The mode of sex determination differed among species. In <i>Oreochromis karongae</i> and <i>Tilapia mariae</i> the sex-determining locus is on linkage group (LG) 3 and the female is heterogametic (WZ-ZZ system). In <i>O. niloticus</i> and <i>T. zillii</i> the sex-determining locus is on LG1 and the male is heterogametic (XX-XY system). A more complex pattern was observed in <i>O. aureus</i> and <i>O. mossambicus</i>, in which markers on both LG1 and LG3 were associated with sex. We found evidence for sex-linked lethal effects on LG1, as well as interactions between loci in the two linkage groups. Comparison of genetic and physical maps demonstrated a broad region of recombination suppression harboring the sex-determining locus on LG3. Sex-specific recombination suppression was found in the female heterogametic sex. Sequence analysis showed the accumulation of repetitive elements in this region. Phylogenetic analysis suggests that at least two transitions in the mode of sex determination have occurred in this clade. This variation in sex determination mechanisms among closely related species makes tilapias an excellent model system for studying the evolution of sex chromosomes in vertebrates.
- Virginia Tech United States
- University of Stirling United Kingdom
- Centre de Coopération Internationale en Recherche Agronomique pour le Développement France
- French National Centre for Scientific Research France
- Sorbonne University France
Male, sex determination, gamète, http://aims.fao.org/aos/agrovoc/c_24847, Aquaculture, Breeding, http://aims.fao.org/aos/agrovoc/c_26822, http://aims.fao.org/aos/agrovoc/c_3185, chromosome, recombination suppression, L53 - Physiologie animale - Reproduction, In Situ Hybridization, Fluorescence, Phylogeny, Recombination, Genetic, détermination du sexe, Sex Chromosomes, Oreochromis, http://aims.fao.org/aos/agrovoc/c_24030, tilapia (genre), Cichlidae, Biological Evolution, heterogametic sex, Phenotype, Female, http://aims.fao.org/aos/agrovoc/c_1598, différenciation sexuelle, Tilapia, Genetic Markers, Genotype, marqueur génétique, 610, paramètre génétique, inversion, Genetic, Species Specificity, http://aims.fao.org/aos/agrovoc/c_7768, Tilapia Genetics, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, phylogénie, Animals, Sex Chromosomes genetics, sex chromosome, http://aims.fao.org/aos/agrovoc/c_13325, http://aims.fao.org/aos/agrovoc/c_36128, http://aims.fao.org/aos/agrovoc/c_6475, http://aims.fao.org/aos/agrovoc/c_26596, Sex Determination Processes, L10 - Génétique et amélioration des animaux, recombinaison, M12 - Production de l'aquaculture, http://aims.fao.org/aos/agrovoc/c_14226
Male, sex determination, gamète, http://aims.fao.org/aos/agrovoc/c_24847, Aquaculture, Breeding, http://aims.fao.org/aos/agrovoc/c_26822, http://aims.fao.org/aos/agrovoc/c_3185, chromosome, recombination suppression, L53 - Physiologie animale - Reproduction, In Situ Hybridization, Fluorescence, Phylogeny, Recombination, Genetic, détermination du sexe, Sex Chromosomes, Oreochromis, http://aims.fao.org/aos/agrovoc/c_24030, tilapia (genre), Cichlidae, Biological Evolution, heterogametic sex, Phenotype, Female, http://aims.fao.org/aos/agrovoc/c_1598, différenciation sexuelle, Tilapia, Genetic Markers, Genotype, marqueur génétique, 610, paramètre génétique, inversion, Genetic, Species Specificity, http://aims.fao.org/aos/agrovoc/c_7768, Tilapia Genetics, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, phylogénie, Animals, Sex Chromosomes genetics, sex chromosome, http://aims.fao.org/aos/agrovoc/c_13325, http://aims.fao.org/aos/agrovoc/c_36128, http://aims.fao.org/aos/agrovoc/c_6475, http://aims.fao.org/aos/agrovoc/c_26596, Sex Determination Processes, L10 - Génétique et amélioration des animaux, recombinaison, M12 - Production de l'aquaculture, http://aims.fao.org/aos/agrovoc/c_14226
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