Celastrol alleviates comorbid obesity and depression by directly binding amygdala HnRNPA1 in a mouse model
Copyright policy ) Chunyan Zhu; Jun Yang; Yongping Zhu; Jiahao Li; Hongyu Chi; Congmin Tian; Yuqing Meng; Yanqing Liu; Jigang Wang; Na Lin;
Celastrol alleviates comorbid obesity and depression by directly binding amygdala HnRNPA1 in a mouse model
Background and Purpose: Obesity and depression are highly comorbid and far from effective treating. Celastrol was reported useful for obesity, but its role in the obesity-depression comorbidity remains unknown. This study aims to investigate the efficacy and associated mechanism of celastrol in this comorbidity.
- PEKING UNION MEDICAL COLLEGE China (People's Republic of)
- ShenZhen People’s Hospital China (People's Republic of)
- Central People's Hospital of Zhanjiang China (People's Republic of)
- China Academy of Chinese Medical Sciences China (People's Republic of)
- Institute of Chinese Materia Medica China (People's Republic of)
Medicine (General), Depression, Heterogeneous Nuclear Ribonucleoprotein A1, Comorbidity, Amygdala, Letter to Editor, Disease Models, Animal, Mice, R5-920, Animals, Obesity, Pentacyclic Triterpenes
Medicine (General), Depression, Heterogeneous Nuclear Ribonucleoprotein A1, Comorbidity, Amygdala, Letter to Editor, Disease Models, Animal, Mice, R5-920, Animals, Obesity, Pentacyclic Triterpenes
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selected citations
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 18
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