To study salt tolerance of wheat genotypes (Triticum durum Desf.) during germination, seeds were grown under laboratory conditions using the roll-tube method. Effects of salt stress on height parameters of roots and shoots, dry and fresh biomass, the amount of malondialdehyde (MDA) and the activity of catalase (CAT) were determined as initial indicators. Development of roots and shoots as well as accumulation of dry biomass was more delayed in the Garagylchyg-2 genotype compared with Barakatli-95 under the influence of NaCl. The tolerance indices of wheat genotypes grown in NaCl solutions with different concentrations (100 mM, 200 mM and 250 mM) were found to be 51%, 64% and 93%, for Garagylchyg-2; 58%, 72%, and 95% for Barakatli-95, respectively. The amount of MDA in leaves were higher and CAT activity lower in Garagylchyg-2 compared with Barakatli-95. It suggests that the Barakatli-95 genotype is more salt tolerant than Garagylchyg-2.