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Article . 2004
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Mathematical Models and Methods in Applied Sciences
Article . 2004 . Peer-reviewed
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EVOLUTION AND MEMORY EFFECTS IN THE HOMOGENIZATION LIMIT FOR ELECTRICAL CONDUCTION IN BIOLOGICAL TISSUES

Evolution and memory effects in the homogenization limit for electrical conduction in biological tissues
Authors: AMAR, Micol; ANDREUCCI, Daniele; P. Bisegna; GIANNI, Roberto;

EVOLUTION AND MEMORY EFFECTS IN THE HOMOGENIZATION LIMIT FOR ELECTRICAL CONDUCTION IN BIOLOGICAL TISSUES

Abstract

We study a problem set in a finely mixed periodic medium, modelling electrical conduction in biological tissues. The unknown electric potential solves standard elliptic equations set in different conductive regions (the intracellular and extracellular spaces), separated by a dielectric surface (the cell membranes), which exhibits both a capacitive and a nonlinear conductive behaviour. Accordingly, dynamical conditions prevail on the membranes, so that the dependence of the solution on the time variable t is not only of parametric character. As the spatial period of the medium goes to zero, the electric potential approaches in a suitable sense a homogenization limit u0, which keeps the prescribed boundary data, and solves the equation [Formula: see text]. This is an elliptic equation containing a term depending on the history of the gradient of u0; the matrices B0, A1 in it depend on the microstructure of the medium. More exactly, we have that, in the limit, the current is still divergence-free, but it depends on the history of the potential gradient, so that memory effects explicitly appear. The limiting equation also contains a term ℱ keeping trace of the initial data.

Country
Italy
Keywords

electrical conduction in biological tissue, homogenization, Dynamical condition; electrical conduction in biological tissues; evolution equation with memory; homogenization, dynamic boundary conditions, dynamical condition; electrical conduction in biological tissues; evolution equation with memory; homogenization, Homogenization in context of PDEs; PDEs in media with periodic structure, Settore MAT/05 - ANALISI MATEMATICA, elliptic system, Settore ICAR/08 - SCIENZA DELLE COSTRUZIONI, Integro-partial differential equations, 515, Biological applications of optics and electromagnetic theory, Nonlinear boundary value problems for linear elliptic equations, electrical conduction in biological tissues, Dynamical condition, Systems of elliptic equations, boundary value problems, evolution equation with memory, Settore ING-IND/34 - BIOINGEGNERIA INDUSTRIALE

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
36
Top 10%
Top 10%
Top 10%
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