
The changes in primordial germ cell (PGC) populations were compared in embryos of two inbred strains of mice-KE and CBA/Kw on 11, 12, 13 and 14 day of foetal life. The number of PGCs did not differ in 11-day embryos of both strains. In 12-day CBA/Kw embryos the proliferation rate of PGCs was higher and the number of PGC was significantly higher than in 12-day KE embryos. However, on subsequent days the PGC proliferation rate decreased in CBA/Kw but rapidly increased in KE embryos, leading to significantly higher number of PGCs in 14-day KE embryos. These differences in proliferation rate between KE and CBA/Kw PGCs can be regarded as the reason of strong selection against CBA/Kw derived gametes observed in KECBA aggregation chimaeras.
Chimera, Histocytochemistry, Stem Cells, Cell Count, Mice, Inbred Strains, Alkaline Phosphatase, Embryonic and Fetal Development, Mice, Germ Cells, Animals, Female, Cell Division
Chimera, Histocytochemistry, Stem Cells, Cell Count, Mice, Inbred Strains, Alkaline Phosphatase, Embryonic and Fetal Development, Mice, Germ Cells, Animals, Female, Cell Division
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 2 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
