
A stepwise resolution of the role of individual genes known to play role in sex determination is presented. Cytogenetic abnormalities e.g. male phenotype with XX and female phenotype with XY gonosomal complements helped substantially to ascertain SRY (Sex region of Y) gene activity to be essential for sex phenotype development control. This control seems to be rather suppressive than activating.
Male, Sex Determination Analysis, Sex Chromosomes, Disorders of Sex Development, Humans, Female, Sex Chromosome Aberrations
Male, Sex Determination Analysis, Sex Chromosomes, Disorders of Sex Development, Humans, Female, Sex Chromosome Aberrations
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