[Mutagenic effect of the food-coloring agents tartrazine and indigo carmine].
Copyright policy [Mutagenic effect of the food-coloring agents tartrazine and indigo carmine].
The authors studied the mutagenic action of the food dyes, tartrazine (both Soviet and imported) and indigocarmine in a microbial model and in warm-blooded animals (linear mice). Determined the toxicity and mutagenic action of the dyes on E. coli, strain K-12, carried out chromosomal analysis of the bone marrow, examined the dominant lethals in CBA X C57BL/6 mice. The recommended daily dose amounts to 400 mg/kg for tartrazine and to 50 mg/kg for indigocarmine with regard to the safety factor equal to 100. The data derived as a result of studying the mutagenic activity of tartrazine manufactured in the USSR and CSSR and indigocarmine paste in 3 experimental models allow the conclusion to be made that the doses of these dyes applied in food industry are fairly safe.
Chromosome Aberrations, Male, Indoles, Mutagenicity Tests, Food Coloring Agents, In Vitro Techniques, Indigo Carmine, Animal Feed, Culture Media, Mice, Inbred C57BL, Mice, Bone Marrow, Karyotyping, Mutation, Escherichia coli, Mice, Inbred CBA, Animals, Azo Compounds, Tartrazine, Mutagens
Chromosome Aberrations, Male, Indoles, Mutagenicity Tests, Food Coloring Agents, In Vitro Techniques, Indigo Carmine, Animal Feed, Culture Media, Mice, Inbred C57BL, Mice, Bone Marrow, Karyotyping, Mutation, Escherichia coli, Mice, Inbred CBA, Animals, Azo Compounds, Tartrazine, Mutagens
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!