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Article . 2020
License: CC BY NC
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[Demodex and ocular surface disease].

Authors: Ben Hadj Salah, Wassim; Baudouin, Christophe; Doan, Serge; Angoulvant, A.; Gottlieb, J.; Bénichou, Jérémie; da Cunha, E.; +3 Authors

[Demodex and ocular surface disease].

Abstract

Demodex is a saprophytic mite of the ocular adnexa, which can in certain circumstances proliferate on the skin of the face and on the eyelid margins. It is involved in facial rosacea (especially in the papulopustular form) and in the development or aggravation of anterior and/or posterior blepharitis or even keratoconjunctivitis, often in association with cutaneous lesions ; the pathophysiology is often multifactorial. Symptoms are non-specific, but the presence of cylindrical sleeves on the eyelashes is very suggestive of infestation, and certain techniques of biomicroscopic examination or imaging, such as confocal microscopy in vivo, allow direct visualization of the parasite. Parasitological examination of the eyelashes can confirm the diagnosis and can be improved by good sampling technique. Eyelid hygiene and oil-based ointments are the cornerstone of treatment. New specific treatments, in particular topical treatments based on tea tree oil, ivermectin, as well as pulsed light therapy and micro-exfoliation of the eyelid margin, can help to reduce the parasitic load and improve symptoms.

Keywords

Blepharitis, Eyelashes, Mites, Blépharite, Huile d'arbre à thé, Ivermectin, Microscopy, Confocal, Ivermectine, Dysfonction meibomienne, Keratoconjunctivitis, Meibomian Glands, Tea tree oil, Hygiene, Demodex, Meibomian gland dysfunction, Tea Tree Oil, [SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs, Rosacea, Rosacée, Animals, Humans, Eye Infections, Parasitic

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    popularity
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Top 10%
Average
Average
Green
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